Cancers | Free Full-Text | Engineering Solutions for Mitigation of Chimeric Antigen Receptor T-Cell Dysfunction
EP3115373A1 - Chimeric antigen receptors with an optimized hinge region - Google Patents
Hinge and Transmembrane Domains of Chimeric Antigen Receptor Regulate Receptor Expression and Signaling Threshold
EP3115373A1 - Chimeric antigen receptors with an optimized hinge region - Google Patents
CD8 Binding of MHC-Peptide Complexes in cis or trans Regulates CD8+ T-cell Responses - ScienceDirect
Incorporation of a hinge domain improves the expansion of chimeric antigen receptor T cells | Journal of Hematology & Oncology | Full Text
Cells | Free Full-Text | Hinge and Transmembrane Domains of Chimeric Antigen Receptor Regulate Receptor Expression and Signaling Threshold
Fine Molecular Tuning of Chimeric Antigen Receptors through Hinge Length Optimization | bioRxiv
Schematic view of the CAR construct. The construct contains a CD8... | Download Scientific Diagram
T cell receptor, CD8 co-receptor and MHC class I molecule. The T cell... | Download Scientific Diagram
Two Families of Hinges IgG-based hinges, derived from IgG1, IgG2, or... | Download Scientific Diagram
The CD8α hinge is intrinsically disordered with a dynamic exchange that includes proline cis-trans isomerization - ScienceDirect
Figure1. Structure of different chimeric antigen receptor (CAR)... | Download Scientific Diagram
The IgG4 hinge with CD28 transmembrane domain improves VHH-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer | Nature Communications
Function of Novel Anti-CD19 Chimeric Antigen Receptors with Human Variable Regions Is Affected by Hinge and Transmembrane Domain
The CD8α hinge is intrinsically disordered with a dynamic exchange that includes proline cis-trans isomerization - ScienceDirect
Chimeric Antigen Receptor T Cells and Hematopoietic Cell Transplantation: How Not to Put the CART Before the Horse - Biology of Blood and Marrow Transplantation
Cells | Free Full-Text | Hinge and Transmembrane Domains of Chimeric Antigen Receptor Regulate Receptor Expression and Signaling Threshold
Hypothesized Models of the CD28 and CD8a Hinge Regions (A) The... | Download Scientific Diagram
Activity of sCAR hinge designs. (A) Cytotoxicity of sCAR-T cells with... | Download Scientific Diagram
Engineering and Design of Chimeric Antigen Receptors - ScienceDirect
Efficient killing of tumor cells by CAR-T cells requires greater number of engaged CARs than TCRs
Crystals | Free Full-Text | Crystal Structure of a Chimeric Antigen Receptor (CAR) scFv Domain Rearrangement Forming a VL-VL Dimer
